Intrarenal distribution of trimethoprim and sulfamethoxazole
نویسندگان
چکیده
منابع مشابه
Tuberculosis and trimethoprim-sulfamethoxazole.
The sulfonamides were the first drugs with antituberculous effects. Their use was abandoned and basically forgotten with the advent of streptomycin and isoniazid combination treatment. There is a widespread belief, apparently based on testing a single isolate on questionable media, that Mycobacterium tuberculosis is resistant to trimethoprim-sulfamethoxazole (TMP-SMX). We saw a complex immunoco...
متن کاملConsiderations when prescribing trimethoprim-sulfamethoxazole.
famethoxazole remains a popular antibiotic because of its low cost, effectiveness and familiarity among clinicians. It is the most frequently prescribed antibiotic for urinary tract infections in Canada. Other indications include treatment of infections caused by Pneumocystis jiroveci, Toxoplasma gondii, Stenotrophomonas maltophilia and community-associated methicillin-resistant Staphylococcus ...
متن کاملTrimethoprim-sulfamethoxazole in murine toxoplasmosis.
The combination trimethoprim-sulfamethoxazole had no greater activity in a murine model of toxoplasmosis than did sulfamethoxazole alone.
متن کاملSpurious sulfamethoxazole-trimethoprim resistance of Salmonella typhi.
Several studies have identified thymidine excess in susceptibility test media as the cause of spurious resistance of various bacteria to sulfamethoxazole-trimethoprim. We document the phenomenon in Salmonella typhi and Salmonella paratyphi-A and demonstrate its occurrence in 3 of 17 (18%) lots of Mueller-Hinton agars now in use in major medical laboratories in Lima, Peru. The findings are parti...
متن کاملTrends in adverse reactions to trimethoprim-sulfamethoxazole.
OBJECTIVE To examine temporal trends of adverse drug reactions (ADRs) associated with trimethoprim-sulfamethoxazole (TMP-SMX) use in children. METHODS We performed a retrospective observational study to characterize TMP-SMX ADRs in children between 2000 and 2009. We completed a chart review at our institution by identifying children diagnosed with TMP-SMX ADRs. To compare local trends to comp...
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ژورنال
عنوان ژورنال: Antimicrobial Agents and Chemotherapy
سال: 1980
ISSN: 0066-4804,1098-6596
DOI: 10.1128/aac.17.3.383